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Impaired Semen Quality in Patients with Chronic Prostatitis
Jens Rosellen1, Florian Dittmar1, Arne Hauptmann1
1Clinic of Urology, Pediatric Urology and Andrology, Justus Liebig University Giessen, Rudolf-Buchheim-Strasse 7, 35392 Giessen, Germany.
Journal of Clinical Medicine
|May 25, 2024
Summary
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) may impair semen quality, with about 25% of patients showing lower parameters than WHO references. Bacteriospermia specifically impacts semen volume in these patients.
Area of Science:
- Andrology
- Urology
- Reproductive Medicine
Background:
- Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition.
- Previous studies on CP/CPPS impact on semen quality yielded contradictory results.
Purpose of the Study:
- To prospectively investigate the effect of CP/CPPS on semen parameters.
- To compare semen parameters in CP/CPPS patients against the WHO 2021 reference group.
Main Methods:
- Prospective cohort study involving 1071 patients with suspected CP/CPPS from 2013-2022.
- Comprehensive andrological examination including semen analysis per WHO 2010 guidelines.
- Comparison of patient semen variables with the WHO 2021 reference group (n~3500).
Main Results:
- Median semen parameters were within normal ranges for all evaluated variables.
- Approximately 25% of patients exhibited values below the fifth percentile of the WHO reference group.
- Bacteriospermia was identified as a factor negatively impacting semen volume.
Conclusions:
- This study represents the largest comparison of semen parameters in CP/CPPS patients against WHO 2021 references.
- Evidence suggests an impairment of conventional semen parameters in individuals with CP/CPPS.
- Bacteriospermia is linked to reduced semen volume in CP/CPPS patients.
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