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Related Concept Videos

Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

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In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
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Infection01:20

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
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Updated: Jun 25, 2025

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes
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Candida auris Outbreaks: Current Status and Future Perspectives.

Silvia De Gaetano1, Angelina Midiri1, Giuseppe Mancuso1

  • 1Mycology Laboratory, Department of Human Pathology, University of Messina, 98125 Messina, Italy.

Microorganisms
|May 25, 2024
PubMed
Summary

Candida auris is a critical fungal pathogen causing severe infections with high mortality. This review details its epidemiology, diagnosis, and resistance, crucial for effective control.

Keywords:
antifungal resistanceidentificationinfection controlnosocomial spreadscreening

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Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Public Health

Background:

  • Candida auris is a critical priority pathogen identified by the World Health Organization (WHO).
  • C. auris infections present high mortality rates (30-72%) and pose diagnostic challenges.
  • The yeast spreads easily in healthcare settings, necessitating effective screening and control.

Purpose of the Study:

  • To provide comprehensive updates on Candida auris.
  • To cover epidemiology, clinical characteristics, and genomic analysis.
  • To discuss identification, resistance, treatment, and prevention strategies.

Main Methods:

  • This is a review article, synthesizing existing research and data.
  • Information was gathered on epidemiology, clinical presentation, and genomic studies.
  • Data on antifungal resistance, treatment, and control measures were compiled.

Main Results:

  • Large-scale epidemiology studies are lacking but C. auris is a growing global concern.
  • Diagnostic challenges exist, hindering early outbreak detection.
  • Antifungal resistance is a significant issue, varying by clade and region.

Conclusions:

  • Effective screening for C. auris colonization is essential for prevention and control.
  • Understanding resistance profiles is key to selecting appropriate therapies.
  • Further research and standardized control measures are needed to combat this pathogen.