Related Experiment Video
Updated: Jun 25, 2026
10:52
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
11.1K
Rare Orbital Involvement Originating from Extranodal Marginal Zone Lymphoma
Yao-Chang Wen1, Tzu-Chuan Huang2, Wen-Chiuan Tsai3
1Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Medicina (Kaunas, Lithuania)
|May 25, 2024
Summary
Extranodal marginal zone lymphoma (EMZL) of the ocular adnexa region (OAR) is rare. A 66-year-old female patient achieved complete remission with R-CVP chemotherapy, avoiding radiotherapy side effects.
Area of Science:
- Hematology
- Oncology
- Ophthalmology
Background:
- Primary lymphomas of the ocular adnexa region (OAR) are uncommon, representing a small fraction of non-Hodgkin lymphomas and extranodal lymphomas.
- Extranodal marginal zone lymphoma (EMZL) can arise in various epithelial tissues, including the OAR.
Observation:
- A case report details a 66-year-old female diagnosed with EMZL of the OAR.
- The patient received six cycles of rituximab, cyclophosphamide, vincristine, and prednisone (R-CVP) chemotherapy.
- Radiotherapy was avoided due to concerns about potential ocular side effects.
Findings:
- The patient achieved and maintained complete remission following R-CVP chemotherapy.
- This treatment approach effectively managed the EMZL of the OAR.
Implications:
- Targeted chemotherapy with R-CVP offers a viable alternative to radiotherapy for OAR EMZL.
- This strategy may help mitigate treatment-related ocular complications, preserving visual function.
Related Concept Videos
01:16Primary Lymphoid Organs
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
01:15Secondary Lymphoid Organs
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...