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Chitosan-2D Nanomaterial-Based Scaffolds for Biomedical Applications.
Atanu Naskar1, Sreenivasulu Kilari1, Sanjay Misra1
1Vascular and Interventional Radiology Translational Laboratory, Division of Vascular and Interventional Radiology, Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Polymers
|May 25, 2024
Summary
Chitosan (CS) and 2D nanomaterial scaffolds show promise for biomedical uses. This review explores their properties, applications, and challenges for clinical use.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Regenerative Medicine
Background:
- Chitosan (CS) is a widely studied biomaterial for scaffolds due to its favorable properties.
- Two-dimensional (2D) nanomaterials like black phosphorus (BP) and molybdenum disulfide (MoS2) offer unique physiochemical characteristics for biomedical applications.
Purpose of the Study:
- To review chitosan-based scaffolds and their combination with 2D nanomaterials for biomedical applications.
- To discuss the advantages, challenges, and future perspectives of these composite scaffolds.
Main Methods:
- Literature review of chitosan scaffolds and 2D nanomaterials.
- Analysis of physiochemical properties and biomedical applications.
- Discussion of clinical implementation challenges.
Main Results:
- CS scaffolds exhibit significant potential in various biomedical fields.
- The integration of 2D nanomaterials enhances the properties of CS scaffolds.
- Existing challenges include toxicity and stability concerns for clinical translation.
Conclusions:
- CS-2D nanomaterial scaffolds hold great promise for advanced biomedical applications.
- Further research is needed to overcome challenges and facilitate clinical utilization.
- Synergistic applications of CS-2D nanomaterial scaffolds are encouraged for future development.
