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Congenital crico-thyroid dysplasia: a comprehensive description
Sirine Ayadi1, Boutheina Hammami2, Nesrine Sallemi2
1Faculty of Medicine of Sfax, Otolaryngology- Head and Neck Surgery Department and Research Laboratory LR23ES01, Habib Bourguiba Hospital, 3029, Sfax, Tunisia. sirine_ayadi@medecinesfax.org.
Summary
This report details the first human case of congenital crico-thyroid dysplasia, a rare laryngeal cartilage malformation. This condition was associated with a right-sided aortic arch and aberrant subclavian artery, highlighting important embryological links.
Area of Science:
- Anatomy
- Embryology
- Medical Case Reports
Background:
- Congenital malformations of the larynx are rare and can present with significant respiratory distress.
- The embryological development of the aortic arch and laryngeal cartilages involves the fourth and sixth pharyngeal arches.
Observation:
- A patient presented with acute dyspnea and chronic hoarseness.
- Laryngoscopy revealed a deviated larynx with submucosal swelling.
- Computed tomography confirmed crico-thyroid dysplasia, a laryngocele, right-sided aortic arch, and aberrant subclavian artery.
Findings:
- This is the first reported case of human congenital crico-thyroid dysplasia.
- The dysplasia was associated with cardiovascular anomalies, specifically a right-sided aortic arch and aberrant subclavian artery.
Implications:
- This case highlights the importance of recognizing rare laryngeal anatomical variations.
- Understanding the embryological basis of these anomalies is crucial for diagnosing associated malformations.
- Early identification and management are essential for patients with complex congenital airway abnormalities.
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