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Retrovirus Life Cycles

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...

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Related Experiment Video

Updated: Jun 25, 2025

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Published on: April 9, 2014

Why not eliminate HTLV-1 while eliminating HIV-1?

Goedele N Maertens¹, Damian F J Purcell², Carolina Rosadas¹

¹Department of Infectious Disease, Imperial College London, London W2 1PG, UK.

Lancet (London, England)

|May 25, 2024

Summary

No abstract available in PubMed .

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