Related Experiment Video
Updated: Jun 25, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
[The effect of pre-, pro- and synbiotics on the carbohydrate and lipid metabolism]
Gyula Tomasics1, László Schandl1, Annamária Polyák1
11 Észak-budai Szent János Centrumkórház, II. Belgyógyászat-Diabetológia Budapest, Diós árok 1-3., 1125 Magyarország.
Abstract:
The prevalence of diabetes and its precursor state – the prediabetes – is exponentially spreading worldwide. More and more data suggest the role of gut microbiome in the pathogenesis of the aforementioned conditions. It is well known that pre-, probiotics, and their combination called synbiotics may influence the composition of the gut microflora. Thus they may play a key role in the progression or retardation of the pathogenetic process of diabetes. It is also supported by more and more observations that different drugs – in particular the antidiabetic drugs − can modify the composition of the microbiome. Based on literary data, the authors review the influencing effects of pre-, pro-, and synbiotics on the carbohydrate and lipid metabolism, as well as their potential role in the pathogenesis of type 1 and type 2 diabetes, and summarize briefly the role of antidiabetic drugs on the gut microbiome composition. Orv Hetil. 2024; 165(21): 803–812.
Related Concept Videos
Overview of Carbohydrate Metabolism
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Oral Hypoglycemic Agents: α-Glucosidase Inhibitors
Acarbose and miglitol are...
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Metabolic States of the Body: The Absorptive State
Introduction to Carbohydrates

