Ingenious fluorescent probes for biogenic amine and their applications in bioimaging and food spoilage detection
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View abstract on PubMed
Summary
This summary is machine-generated.New hybrid probes detect biogenic amines, crucial markers of food spoilage. This innovation offers a simple method for real-time food freshness monitoring, enhancing food safety.
Area Of Science
- Analytical Chemistry
- Food Science
- Biochemistry
Background
- Biogenic amines are key indicators of food spoilage, necessitating accurate detection methods for food quality control.
- Current methods for amine detection can be complex and time-consuming, limiting their application in real-time food monitoring.
Purpose Of The Study
- To develop novel fluorescent probes for sensitive and selective detection of biogenic amines.
- To establish a visual method for assessing food spoilage based on probe response.
Main Methods
- Synthesis of two coumarin-difluoroboron β-diketonate hybrid probes (1 and 2) with donor-acceptor-donor configurations.
- Investigation of probe photophysical properties, including solvatochromism and response to amines via intramolecular charge transfer.
- Application of probes for imaging amines in live cells and liver tissues, and for visual food spoilage detection.
Main Results
- Probes 1 and 2 exhibited significant changes in absorption and fluorescence upon reaction with amines due to boron-nitrogen interaction.
- Successful imaging of amines in biological samples (live cells, liver tissues).
- Established a correlation between color changes in probe-loaded food extracts and food storage time, indicating spoilage.
Conclusions
- The developed coumarin-difluoroboron hybrid probes provide a sensitive and convenient platform for amine detection.
- These probes offer a promising strategy for real-time monitoring of food freshness and spoilage.
- The visual detection method based on color change simplifies food quality assessment.
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