Clinical, sociodemographic and environmental predicting factors for relapse in bipolar disorder: A systematic review
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View abstract on PubMed
Summary
This summary is machine-generated.Identifying risk factors for bipolar disorder (BD) relapses is key. Factors like family history, early onset, and unemployment are linked to worse outcomes, aiding in high-risk patient identification.
Area Of Science
- Psychiatry and Mental Health
- Clinical Psychology
- Epidemiology
Background
- Bipolar disorder (BD) is a chronic, relapsing condition.
- Identifying prognostic factors for relapse is crucial for managing BD.
- Understanding risk factors aids in identifying high-risk individuals.
Purpose Of The Study
- To systematically review literature on sociodemographic, clinical, and environmental factors impacting BD relapses.
- To analyze factors associated with clinical relapses, recurrences, and hospitalizations in BD patients.
Main Methods
- Systematic literature search of PubMed, Cochrane Library, and Web of Science.
- Inclusion of 58 articles meeting predefined criteria.
- Grouping studies by assessed risk factor types.
Main Results
- Family/personal psychiatric history, severe episodes, early onset, rapid cycling, low functioning, and cognitive issues predict relapses.
- Unemployment, low education, poor social adjustment, and life events increase episode frequency.
- Cannabis use is linked to higher rehospitalization rates.
Conclusions
- Several factors are associated with poorer BD prognosis, enabling identification of high-risk patients.
- Modifiable risk factors offer potential therapeutic targets.
- Further research is needed to clarify the impact of specific risk factors.
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