Surgical treatment for pulmonary metastasis from ovarian cancer: a retrospective case series
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View abstract on PubMed
Summary
This summary is machine-generated.Pulmonary metastasectomy for ovarian cancer is rare. While all patients survived over 30 months, recurrence was common, suggesting elevated CA125 levels may contraindicate surgery.
Area Of Science
- Oncology
- Surgical Oncology
- Gynecologic Oncology
Background
- Pulmonary metastases from ovarian cancer are uncommon and surgical intervention effectiveness is uncertain.
- This study investigates clinicopathologic features and outcomes of ovarian cancer patients undergoing pulmonary metastasis resection.
Purpose Of The Study
- To evaluate the outcomes of surgical resection for pulmonary metastases in ovarian cancer patients.
- To identify potential predictive factors for successful pulmonary metastasectomy in ovarian cancer.
Main Methods
- Retrospective analysis of 537 patients undergoing pulmonary metastasis resection.
- Inclusion of four ovarian cancer patients who underwent radical surgery for pulmonary metastases between 2010-2021.
- Analysis of patient demographics, time to metastasis, survival, recurrence, and preoperative CA125 levels.
Main Results
- Four patients (0.74%) underwent pulmonary metastasectomy for ovarian cancer.
- Survival post-pulmonary metastasectomy ranged from 34 to 94 months.
- Three patients recurred post-surgery; elevated CA125 levels were observed in deceased patients.
Conclusions
- Pulmonary metastasectomy in ovarian cancer patients resulted in long-term survival but frequent recurrence.
- Elevated preoperative CA125 levels may indicate poor candidacy for pulmonary metastasectomy.
- Larger cohort studies are needed to establish criteria for pulmonary metastasectomy in ovarian cancer.
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