Ulcerated nodules with zosteriform distribution on the upper extremity.

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Eccrine porocarcinoma (EPC) is a rare malignant neoplasm of the skin's adnexal glands.
• EPC has a significant metastatic potential, commonly affecting lymph nodes and lungs.
• Cutaneous metastasis of EPC is exceptionally rare, with the zosteriform pattern being exceedingly uncommon.

Observation:

• A unique case of EPC with zosteriform cutaneous metastasis is presented.
• The patient, a 71-year-old male, exhibited multiple ulcerated nodules in a zosteriform distribution on his upper left limb.
• Associated findings included lymphatic metastases and lymphedema.

Findings:

• This case represents one of the few documented instances of zosteriform cutaneous metastasis from EPC.
• The clinical presentation highlights an unusual pattern of disease spread for this rare malignancy.
• The findings underscore the diverse metastatic potential of eccrine porocarcinoma.

Implications:

• This case expands the understanding of EPC's metastatic behavior.
• It emphasizes the importance of considering rare presentations in the differential diagnosis of cutaneous lesions.
• Further research into the mechanisms and management of rare metastatic patterns of EPC is warranted.