Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A wireless subdural-contained brain-computer interface with 65,536 electrodes and 1,024 channels.

Nature electronics·2026
Same author

Visual uncertainty and task demands shape active sensing strategies in mice.

bioRxiv : the preprint server for biology·2026
Same author

A Conformable CMOS Ultrasound System for Point-of-Care Imaging.

medRxiv : the preprint server for health sciences·2026
Same author

A Single Institution Experience with Pancreatic Carcinoma: A Retrospective Study.

Indian journal of surgical oncology·2026
Same author

Minimally invasive approach for excision of left atrial myxoma-an 8-year single-center experience.

Indian journal of thoracic and cardiovascular surgery·2026
Same author

Innovative Technique for Single-Stage Phalloplasty with Complete Urethral Reconstruction for Micropenis and Perineal Hypospadias.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India·2026

Related Experiment Video

Updated: Jun 25, 2025

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice
08:42

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice

Published on: July 26, 2024

1.0K

Stable, chronic in-vivo recordings from a fully wireless subdural-contained 65,536-electrode brain-computer interface

Taesung Jung1, Nanyu Zeng1, Jason D Fabbri1

  • 1Department of Electrical Engineering, Columbia University; New York, NY 10027, USA.

Biorxiv : the Preprint Server for Biology
|May 27, 2024
PubMed
Summary
This summary is machine-generated.

Researchers developed a flexible, high-density micro-electrocorticography (μECoG) brain-computer interface (BCI) for advanced neural recording. This minimally invasive device offers high-bandwidth, reliable brain signal decoding for future human applications.

More Related Videos

Simultaneous Recordings of Cortical Local Field Potentials, Electrocardiogram, Electromyogram, and Breathing Rhythm from a Freely Moving Rat
10:07

Simultaneous Recordings of Cortical Local Field Potentials, Electrocardiogram, Electromyogram, and Breathing Rhythm from a Freely Moving Rat

Published on: April 2, 2018

10.9K
Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs
08:30

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Published on: March 31, 2023

2.6K

Related Experiment Videos

Last Updated: Jun 25, 2025

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice
08:42

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice

Published on: July 26, 2024

1.0K
Simultaneous Recordings of Cortical Local Field Potentials, Electrocardiogram, Electromyogram, and Breathing Rhythm from a Freely Moving Rat
10:07

Simultaneous Recordings of Cortical Local Field Potentials, Electrocardiogram, Electromyogram, and Breathing Rhythm from a Freely Moving Rat

Published on: April 2, 2018

10.9K
Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs
08:30

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Published on: March 31, 2023

2.6K

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Materials Science

Background:

  • Brain-computer interfaces (BCIs) are crucial for human applications.
  • Existing BCI technologies face limitations in volumetric efficiency and invasiveness.
  • Advancements in miniaturization and integration are needed for next-generation BCIs.

Purpose of the Study:

  • To develop a minimally invasive, high-bandwidth BCI with improved volumetric efficiency.
  • To create a flexible micro-electrocorticography (μECoG) device with a high density of recording channels.
  • To demonstrate chronic, reliable neural recordings and signal decoding in animal models.

Main Methods:

  • Fabrication of a 50-μm-thick, flexible μECoG BCI on a CMOS substrate.
  • Integration of a 256x256 electrode array (65,536 channels) with signal processing, telemetry, and wireless powering.
  • Implantation below the dura in pigs and non-human primates for chronic recordings.
  • Bidirectional wireless communication with an external relay station.

Main Results:

  • Achieved orders-of-magnitude improvement in volumetric efficiency compared to other BCI technologies.
  • Demonstrated chronic, reliable recordings for up to 2 weeks in pigs and 2 months in non-human primates.
  • Successfully decoded brain signals from somatosensory, motor, and visual cortices at high spatiotemporal resolution.

Conclusions:

  • The developed μECoG BCI represents a significant advancement in neural interface technology.
  • The device enables minimally invasive, high-bandwidth brain signal acquisition and decoding.
  • This technology holds potential for revolutionizing human applications requiring advanced brain-computer interaction.