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Normative Computed Tomography Angiography Values of the Aortic Root, Aorta and Aortic arch in Children

Rakesh Donthula1, Wen Li1, Archita Duvvada2

  • 1the University of Texas McGovern Medical School at Houston.

Research Square
|May 27, 2024
PubMed

Insights

This study provides essential normative values for children's aortic structures using ECG-gated CTA. These findings establish crucial reference ranges for normal growth and development in pediatric cardiovascular imaging.

Area of Science:

  • Pediatric cardiovascular imaging
  • Medical imaging analysis
  • Biomedical engineering

Background:

  • Normative data for intracardiac and extracardiac vascular structures are vital for assessing pediatric growth.
  • Current normative data for ECG-gated Computed Tomography Angiography (CTA) are lacking.
  • Establishing these values aids in understanding normal cardiovascular development in children.

Purpose of the Study:

  • To establish normative values for the aortic root, aorta, and aortic arch in children using ECG-gated CTA.
  • To provide a reference dataset for pediatric cardiovascular assessment.
  • To facilitate the interpretation of cardiovascular imaging in pediatric patients.

Main Methods:

  • Measurements of the aortic root, ascending aorta, aortic arch, and descending aorta were taken in systole and diastole from 100 pediatric subjects.
  • ECG-gated CTA scans were utilized for precise vascular measurements.
  • Allometric exponent (AE) and body surface area (BSA^AE) normalization methods were applied to derive standardized values.

Main Results:

  • Systolic and diastolic ECG-gated CTA Z-scores were calculated for the aortic root, aorta, and aortic arch.
  • Normative curves were generated, plotting measurements in relation to Body Surface Area (BSA).
  • Normalized mean, cross-sectional area, and standard deviation were computed for all measured parameters.

Conclusions:

  • The study successfully reports systolic and diastolic ECG-gated CTA Z-scores for pediatric aortic structures.
  • Normative curves relative to BSA have been established for the aortic root, aorta, and aortic arch.
  • These findings provide essential reference data for pediatric cardiovascular imaging and clinical assessment.
Abstract

Keywords:
AortaAortic rootComputed Tomography AngiographyNormative valuesPediatricsZ-scores

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