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Modernizing and harmonizing regulatory data requirements for genetically modified crops-perspectives from a workshop.

Nicholas P Storer1, Abigail R Simmons2, Jordan Sottosanto3

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Frontiers in Bioengineering and Biotechnology
|May 27, 2024
PubMed
Summary

Modernizing genetically modified (GM) crop regulations can streamline commercialization. A workshop proposed a science-based approach, reducing data requirements for GM crops and benefiting growers, consumers, and the environment.

Keywords:
cultivationdata requirementsenvironmental risk assessment (ERA)food and feedgenetically modified (GM)problem formulationregulationsafety assessment

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Area of Science:

  • Agricultural biotechnology
  • Regulatory science
  • Biosafety research

Background:

  • Genetically modified (GM) crops have been commercially available since 1995, with widespread global cultivation.
  • Despite documented benefits and a strong safety record, regulatory scrutiny for GM crops has intensified, increasing burdens and fostering distrust.
  • Existing regulatory frameworks may not fully reflect the scientific advancements in GM crop development.

Purpose of the Study:

  • To examine the scientific basis for modernizing global regulatory frameworks for genetically modified (GM) crops.
  • To propose recommendations for a streamlined, science-based data package for GM crop safety assessments.
  • To explore how modernized data requirements can facilitate timely commercialization and innovation in GM crop technology.

Main Methods:

  • A workshop was convened at the 16th International Society of Biosafety Research (ISBR) Symposium, gathering diverse global stakeholders.
  • Participants discussed recommendations for a core set of data and supplementary data based on case-by-case risk assessment.
  • A case study involving hypothetical GM maize with insect protection and herbicide tolerance traits was used to evaluate proposed data requirements.

Main Results:

  • Discussions indicated that current data requirements for GM crop safety assessments could be modernized.
  • A science-based approach using a core and conditional data set was deemed feasible for evaluating GM crops.
  • Modernized data packages could potentially accelerate the regulatory process for GM crops.

Conclusions:

  • Modernizing GM crop regulatory frameworks based on scientific evidence can reduce burdens on regulators and developers.
  • A more efficient regulatory system would enable faster commercialization of GM crops, fostering innovation.
  • Adopting modernized approaches globally can enhance the benefits of GM crops for agriculture, consumers, and the environment.