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Updated: Jun 25, 2025

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
Published on: October 30, 2018
Path toward "Net Zero Organic Synthesis"
Prathama S Mainkar1, Srivari Chandrasekhar1
1CSIR- Indian Institute of Chemical Technology, Hyderabad 500007, India.
Ideal synthesis aims for perfect molecular creation, aligning with the Net Zero concept for sustainable organic chemistry. This viewpoint explores principles and strategies for environmentally conscious molecular synthesis.
Area of Science:
- Organic Chemistry
- Green Chemistry
- Sustainable Synthesis
Background:
- Molecular synthesis has advanced significantly over 200 years, yet the concept of 'ideal synthesis' remains underdeveloped.
- The 'Net Zero' concept is gaining traction across various technological fields, offering a new perspective for chemical synthesis.
Purpose of the Study:
- To review and discuss the established principles of ideal synthesis.
- To explore the integration of the Net Zero concept into organic molecule synthesis.
- To enhance the acceptance and perception of organic chemistry by addressing environmental concerns.
Main Methods:
- Literature review of ideal synthesis principles.
- Conceptual framework for applying Net Zero principles to organic synthesis.
- Discussion of strategies for environmentally benign molecular construction.
Main Results:
- Identified key principles of ideal synthesis.
- Proposed a framework for Net Zero-aligned organic synthesis.
- Highlighted the potential for improved public perception of chemistry.
Conclusions:
- Integrating Net Zero principles can advance the concept of ideal synthesis.
- Sustainable practices are crucial for the future of organic chemistry.
- Addressing environmental impact is key to broader acceptance of the field.
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