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Updated: Jun 25, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Sickle Cell Disease With Ulcerative Colitis in An Ethiopian Child
Abebe Habtamu Tamire1, Tenagne Million2
1Department of Pediatrics and Child Health, Addis Ababa University, College of Health Sciences, Addis Ababa, Ethiopia.
Abstract:
Sickle cell disease (SCD) is a hereditary blood disorder characterized by abnormal hemoglobin, resulting in various clinical manifestations. Recognizing the complex clinical picture of SCD is crucial for physicians to effectively diagnose and manage the disease. While typical presentations may be absent, it is important to consider the possibility of SCD in patients presenting with ulcerative colitis (UC). The concurrent occurrence of UC and SCD is extremely rare. Therefore, a comprehensive investigation is warranted for individuals at risk of developing SCD with UC. In this report, we presented the first documented case of a child in Ethiopia with both SCD and UC.
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