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Ex vivo model for pre-clinical evaluation of dialyzers containing new membranes
A Mahiout1, H Meinhold, A Jörres
1Klinikum Charlottenburg, Dept of Nephrology, Free University Berlin.
Life Support Systems : the Journal of the European Society for Artificial Organs
|January 1, 1985
Abstract:
The ex vivo model which reflects hemodialysis modulating factors during the first twenty minutes of blood membrane interaction, is applicable as a pre-clinical test for new membranes. The biocompatibility of a new cellulosic membrane (MC) proved to be superior to regenerated cellulose and comparable to synthetic membranes such as PAN regarding complement activation.