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Out-of-hospital cardiac arrest in children in Norway: A national cohort study, 2016-2021
Inga Katherina Kelpanides1,2, Stephan Katzenschlager3, Eirik Skogvoll4,5
1Department of Research & Development, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.
Insights
Out-of-hospital cardiac arrest (OHCA) in children is rare but serious, with choking and respiratory issues being leading causes. Infants under one year face the highest risk, highlighting the need for focused prevention and infant care strategies.
Area of Science:
- Pediatrics
- Emergency Medicine
- Public Health
Background:
- Out-of-hospital cardiac arrest (OHCA) in children is a critical medical emergency.
- Understanding the specific incidence, causes, and outcomes of pediatric OHCA is vital for targeted interventions.
- Children represent a distinct patient group with unique needs during cardiac arrest events.
Purpose of the Study:
- To determine the age-specific incidence of pediatric OHCA.
- To identify the primary causes and circumstances surrounding pediatric OHCA.
- To evaluate the outcomes of pediatric OHCA to inform prevention and treatment strategies.
Main Methods:
- A population-based cohort study utilizing data from the Norwegian Cardiac Arrest Registry.
- Analysis of data from 2016-2021 for individuals under 18 years of age.
- Descriptive statistics were used to report incidence, causes, treatment, and outcomes.
Main Results:
- The incidence of pediatric OHCA was 4.6 per 100,000 child-years, significantly higher in infants (<1 year) at 20.9 per 100,000 child-years.
- Leading causes included choking, cardiac and respiratory diseases, and sudden infant death syndrome.
- Overall survival to 30 days was 21%, and to one year was 18%.
Conclusions:
- Pediatric OHCA characteristics differ from adults, with infants <1 year being a high-risk group.
- Effective prevention and treatment strategies should focus on infant care, bystander first aid, and early identification of at-risk children.
- Cardiac arrest registries are crucial for advancing research and improving care for pediatric cardiac arrest.
Aim:
Children constitute an important and distinct subgroup of out-of-hospital cardiac arrest (OHCA) patients. This population-based cohort study aims to establish current age-specific population incidence, precipitating causes, circumstances, and outcome of paediatric OHCA, to guide a focused approach to prevention and intervention to improve outcomes.
Methods:
Data from the national Norwegian Cardiac Arrest Registry was extracted for the six-year period 2016-21 for persons aged <18 years. We present descriptive statistics for the population, resuscitation events, presumed causes, treatment, and outcomes, alongside age-specific incidence and total paediatric mortality rates.
Results:
Three hundred and eight children were included. The incidence of OHCA was 4.6 per 100 000 child-years and markedly higher in children <1 year at 20.9 child-years. Leading causes were choking, cardiac and respiratory disease, and sudden infant death syndrome. Overall, 21% survived to 30 days and 18% to one year.
Conclusion:
A registry-based approach enabled this study to delineate the characteristics and trajectories of OHCA events in a national cohort of children. Precipitating causes of paediatric OHCA are diverse compared to adults. Infants aged <1 year are at particularly high risk. Mortality is high, albeit lower than for adults in Norway. A rational community approach to prevention and treatment may focus on general infant care, immediate first aid by caretakers, and identification of vulnerable children by primary health providers. Cardiac arrest registries are a key source of knowledge essential for quality improvement and research into cardiac arrest in childhood.
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