A National Analysis of Alcohol Withdrawal Syndrome in Patients with Operative Trauma
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View abstract on PubMed
Summary
This summary is machine-generated.Alcohol withdrawal syndrome (AWS) in trauma patients increases mortality, complications, and costs. Identifying risk factors like male sex and head injury can improve screening and care.
Area Of Science
- Trauma Surgery
- Critical Care Medicine
- Addiction Medicine
Background
- Alcohol withdrawal syndrome (AWS) complicates postoperative management, especially in trauma patients.
- Screening for AWS in critically injured patients is challenging due to subjective assessments.
- Identifying predictors of AWS in trauma is crucial for optimizing care.
Purpose Of The Study
- To identify patient characteristics and perioperative outcomes associated with AWS development in trauma patients.
- To analyze the impact of AWS on mortality, complications, and resource utilization in trauma care.
- To inform the development of improved screening protocols for AWS in trauma settings.
Main Methods
- Analysis of the 2016-2020 National Inpatient Sample for adult trauma hospitalizations.
- Inclusion of non-elective operative trauma cases with AWS diagnosis, excluding traumatic brain injury and short stays.
- Outcomes assessed included in-hospital mortality, complications, costs, length of stay (LOS), and discharge disposition.
Main Results
- 1.23% of operative trauma hospitalizations (36,415/2,965,079) developed AWS.
- AWS was linked to increased mortality (AOR 1.46), infectious (AOR 1.73), cardiac (AOR 1.24), and respiratory (AOR 1.96) complications.
- AWS correlated with prolonged LOS (+3.3 days), higher costs (+$8900), and non-home discharge (AOR 1.43). Male sex, Medicaid status, head injury, and thoracic surgery predicted AWS development.
Conclusions
- AWS development in trauma patients is associated with significantly increased in-hospital mortality.
- AWS leads to a greater burden of perioperative complications and increased healthcare resource utilization.
- Identifying specific patient and operative factors associated with AWS can enhance early detection and management in trauma care.
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