Related Experiment Video
Updated: Jun 25, 2025

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Cocaine-Induced Chronic Bowel Ischemia Manifesting As Small Bowel Obstruction
Iraklis Perysinakis1, Georgios Saridakis1, Miltiadis Giannarakis2
1Department of Surgical Oncology, University Hospital of Heraklion, Heraklion, GRC.
Abstract:
Cocaine represents one of the most frequently used recreational drugs worldwide. Cocaine-related disorders mostly affect the nervous and cardiovascular system, although gastrointestinal complications are not negligible and sometimes life-threatening. The most common gastrointestinal manifestations of cocaine abuse are ulceration, infarction, perforation, ischemic enterocolitis, and rarely hemorrhage, with mesenteric ischemia being the underlying pathophysiological mechanism. Herein, we report a rare case of cocaine-induced small bowel obstruction in a young female patient, caused by chronic mesenteric ischemia and excessive intestinal wall fibrosis.
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