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Updated: Jun 25, 2025
Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
Published on: January 27, 2018
Modified platelet rich plasma therapy for alopecia totalis
Avita Dhiman1, Manmohan Bagri1
1Department of Dermatology, Venereology and Leprology; All India Institute of Medical Sciences, Rishikesh, Uttarakhand-249203, India.
Platelet-rich plasma (PRP) therapy, combined with intralesional triamcinolone acetonide, shows promise for treating alopecia totalis. This approach may help patients reduce their reliance on oral immunosuppression.
Area of Science:
- Dermatology
- Immunology
- Regenerative Medicine
Background:
- Alopecia areata (AA) is an autoimmune condition causing nonscarring hair loss.
- Alopecia totalis, a severe form of AA, has a generally poor prognosis.
Observation:
- A modified Platelet-rich plasma (PRP) therapy was administered.
- Intralesional triamcinolone acetonide was used in conjunction with PRP.
Findings:
- The combined therapy demonstrated significant benefits for patients with alopecia totalis.
- This treatment approach facilitated the reduction of oral immunosuppressive medications.
Implications:
- Modified PRP therapy offers a potential therapeutic strategy for severe alopecia areata.
- This treatment may improve patient outcomes and reduce systemic side effects from long-term immunosuppression.
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