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Related Concept Videos

Physiological Barriers01:25

Physiological Barriers

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Physiological barriers are semi-permeable cellular structures restricting drug diffusion into intracellular compartments and tissues. There are six types of physiological barriers: blood endothelial, cell membrane, blood-brain, blood-cerebrospinal fluid (CSF), blood-placenta, and blood-testis barriers.
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Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

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Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
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In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
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Formation of the Platelet Plug01:22

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The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
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Positive and Negative Feedback Loops01:18

Positive and Negative Feedback Loops

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Animal organs and organ systems constantly adjust to internal and external changes through a process called homeostasis ("steady state"). Examples of these changes include regulation of the level of glucose or calcium in the blood or internal responses to external temperatures. Homeostasis requires  maintaining an internal dynamic equilibrium:
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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Updated: Jun 25, 2025

Author Spotlight: Advancing Research Through Single Cell Sequencing and Spatial Histology in Placental Tissues
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Physiological plateaus during normal labor and birth: A novel definition.

Marina Weckend1, Kylie McCullough1, Christine Duffield1,2

  • 1School of Nursing and Midwifery, Edith Cowan University, Joondalup, Western Australia, Australia.

Birth (Berkeley, Calif.)
|May 27, 2024
PubMed
Summary
This summary is machine-generated.

Physiological plateaus, a temporary labor slowdown, are common and may be misinterpreted as dystocia. Recognizing these self-regulatory events can help de-medicalize childbirth and prevent unnecessary interventions.

Keywords:
failure to progresslabor dystocialabor progressmidwiferynatural childbirthnormal birthuterine inertia

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Area of Science:

  • Maternal-fetal medicine
  • Obstetrics
  • Midwifery

Background:

  • Labor dystocia and augmentation contribute significantly to childbirth medicalization.
  • Labor dystocia lacks a clear definition, and physiological plateaus are under-researched.
  • Understanding physiological plateaus is crucial for contemporary maternity care.

Purpose of the Study:

  • To define physiological plateaus in childbirth.
  • To establish a foundation for further research into physiological plateaus.

Main Methods:

  • Qualitative study using grounded theory.
  • Interviews with 20 Australian midwives (September 2020 - February 2022).
  • Three-phase coding: inductive line-by-line, thematic analysis, and axial coding.

Main Results:

  • Physiological plateaus are temporary, common labor slowdowns, lasting minutes to hours.
  • They appear to be a self-regulatory mechanism of the mother-infant dyad.
  • Plateaus self-resolve, leading to labor resumption and positive birth outcomes.

Conclusions:

  • Physiological plateaus are common but under-recognized in childbirth.
  • Misinterpretation as labor dystocia risks unnecessary augmentation.
  • Further research is needed, but the proposed definition aids de-medicalization efforts.