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What constitutes an obstructive ventilatory impairment in a pediatric population? A study design

Mariem Abdesselem1,2, Nadia Ben Lazreg1,2, Helmi Ben Saad1,2

  • 1University of Sousse, Farhat Hached hospital. Laboratory of physiology and functional explorations, Sousse, Tunisia.

La Tunisie Medicale
|May 27, 2024
PubMed

Insights

The definition of obstructive ventilatory impairment (OVI) in children varies significantly by diagnostic criteria. This study highlights how different spirometry interpretations impact OVI prevalence in pediatric patients.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Clinical Diagnostics

Background:

  • Obstructive ventilatory impairment (OVI) lacks a standardized definition in pediatric populations.
  • Existing international guidelines offer varied criteria for diagnosing OVI in children and adolescents.

Purpose of the Study:

  • To compare the prevalence of OVI in children and adolescents using six distinct international definitions.
  • To assess the impact of different spirometry interpretation criteria on OVI diagnosis in a pediatric cohort.

Main Methods:

  • A bi-centric cross-sectional study was conducted on 6-18 year olds in Sousse, Tunisia.
  • Spirometry data was collected using standardized equipment.
  • Six different OVI definitions from various international societies (GINA, ICGP, ERS-ATS, NICE, CTS, ERS) were applied.

Main Results:

  • The study anticipates a significant variation in the calculated percentage of pediatric patients with OVI across the six applied definitions.
  • The prevalence of OVI is expected to be definition-dependent.

Conclusions:

  • The frequency of diagnosing obstructive ventilatory impairment in children is contingent upon the specific definition employed.
  • Establishing a consensus on OVI definition in pediatric spirometry is crucial for consistent diagnosis and management.
Abstract

Keywords:
AlgorithmAsthmaBTSERS/ATSFEV1/FVC ratioGINAHealth problemInterpretationLung function testScholarly societies

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