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Updated: Aug 6, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Obstructive sleep apnea induced by a parapharyngeal cystic hygroma in an infant
Insights
A rare neck tumor caused severe obstructive sleep apnea in an infant. Surgical removal resolved the condition, highlighting the need for thorough diagnosis in pediatric sleep apnea.
Area of Science:
- Pediatric Sleep Medicine
- Otolaryngology
- Medical Genetics
Background:
- Obstructive sleep apnea (OSA) in infants can stem from various causes, including anatomical abnormalities.
- Early diagnosis and intervention are crucial for managing severe pediatric OSA and preventing long-term health issues.
Observation:
- A 7-week-old infant presented with severe obstructive sleep apnea, documented by polysomnography showing 455 obstructive apneas nightly, averaging 34 seconds each.
- A parapharyngeal cystic hygroma, a neck tumor, was identified as the underlying cause of the infant's severe obstructive sleep apnea.
Findings:
- Surgical excision of the parapharyngeal cystic hygroma led to a dramatic improvement in the infant's condition.
- Follow-up polygraphic recordings normalized, and the infant remained stable for 10 months post-surgery, indicating a complete resolution of OSA.
Implications:
- This case highlights cystic hygromas as a rare but significant cause of severe obstructive sleep apnea in infants.
- Emphasizes the importance of a comprehensive diagnostic approach to identify and treat the root causes of pediatric obstructive sleep apnea.
Abstract:
A 7-week-old infant with severe sleep apnea underwent polysomnography that revealed as many as 455 obstructive apneas per night; the apneic episodes had a mean duration of 34 s. A growing tumor in the neck, a parapharyngeal cystic hygroma, was discovered and surgically removed. The infant's condition improved dramatically, and a follow-up polygraphic recording was normal. During the following 10 months the child's condition remained stable. The case reported illustrates a rare cause of severe sleep obstructive apnea. It also reinforces the need for a complete medical approach to the diagnosis and treatment of obstructive sleep apnea in infants.
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