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PEGASE: a machine language program for DNA sequence analysis on Apple II microcomputer using a binary coding of

F Dardel1

  • 1Laboratoire de Biochimie, Ecole polytechnique, Palaiseau, France.

Computer Applications in the Biosciences : CABIOS
|January 1, 1985
PubMed
Summary
This summary is machine-generated.

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This study introduces a 6502 machine language program for DNA sequence analysis on Apple II computers. It enables efficient, interactive data handling on low-cost systems, rivaling larger computer performance.

Area of Science:

  • Bioinformatics
  • Computer Science
  • Molecular Biology

Background:

  • DNA sequence analysis is crucial for biological research.
  • High-performance computing is often required for DNA analysis.
  • Limited access to advanced computational resources can hinder research.

Purpose of the Study:

  • To describe a 6502 machine language program for DNA sequence analysis.
  • To enable interactive data manipulation on low-cost microcomputers.
  • To provide an accessible tool for routine sequence handling and experiment design.

Main Methods:

  • Development of a 6502 machine language program.
  • Implementation of binary coding for nucleotide representation.
  • Utilizing the Apple II microcomputer platform.

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Main Results:

  • The program facilitates interactive data manipulation for DNA sequences.
  • Execution times are comparable to those of larger, more expensive computers.
  • The system offers a cost-effective solution for sequence analysis.

Conclusions:

  • The PEGASE system provides an efficient and user-friendly method for DNA sequence analysis.
  • This approach democratizes access to computational tools in molecular biology.
  • The system is suitable for routine tasks and experimental planning in biological research.