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SEQ-ED: an interactive computer program for editing, analysis and storage of long DNA sequences.
1Department of Tumor Biology, Karolinska Institute, Stockholm, Sweden.
Computer Applications in the Biosciences : CABIOS
|January 1, 1985
Summary
SEQ-ED is a new computer program designed for efficient DNA sequence analysis and storage. It handles long DNA sequences using a compressed format, minimizing storage needs for molecular biologists.
Area of Science:
- Bioinformatics
- Computational Biology
- Genomics
Background:
- The increasing volume of DNA sequence data necessitates efficient computational tools for management and analysis.
- Existing methods may require significant storage space, posing challenges for large-scale genomic projects.
Purpose of the Study:
- To introduce SEQ-ED, a novel software program for handling and storing large DNA sequence datasets.
- To provide molecular biologists with an accessible tool for DNA sequence management, regardless of their computer expertise.
Main Methods:
- Development of a program, SEQ-ED, capable of managing numerous DNA sequences up to 200 kilobases.
- Implementation of a compressed storage format utilizing three binary digits per base to reduce storage requirements.
Main Results:
- SEQ-ED efficiently stores and manages a substantial number of long DNA sequences.
- The program's compressed format significantly minimizes the required storage space.
Conclusions:
- SEQ-ED offers an effective solution for the storage and analysis of large DNA sequence libraries.
- The user-friendly design of SEQ-ED empowers molecular biologists to manage genomic data effectively.