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Appendiceal Signet Ring Cell Carcinoma Presenting As Acute Appendicitis: A Case Report
Emily A Ina1, Alexandria Sobczak1, Konrad Drzymalski1
1Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Cureus
|May 28, 2024
Summary
Appendiceal signet ring cell carcinoma is a rare cause of abdominal pain, often mimicking appendicitis. Early detection and treatment are crucial for this aggressive cancer with a poor prognosis.
Area of Science:
- Gastroenterology
- Oncology
Background:
- Appendiceal signet ring cell carcinoma (ASRCA) is a rare malignancy, accounting for only 4% of all appendix carcinomas.
- ASRCA can present with symptoms similar to acute appendicitis, leading to diagnostic challenges.
Observation:
- A case report details a 77-year-old female presenting with right lower quadrant abdominal pain.
- Diagnostic workup, including exploratory laparoscopy and histopathology, revealed peritoneal carcinomatosis and ASRCA.
Findings:
- ASRCA is characterized by its aggressive nature and a generally poor prognosis.
- The study highlights the importance of considering ASRCA in the differential diagnosis of abdominal pain.
Implications:
- This case underscores the need for heightened awareness and early diagnostic intervention for ASRCA.
- Further research into the etiology, prevalence, and optimal treatment strategies for ASRCA is warranted.
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