Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reversible parkinsonism from shunt failure.

M E Brazin1, L G Epstein

  • 1Department of Neurosciences, UMDNJ-New Jersey Medical School, Newark 07103.

Pediatric Neurology
|September 1, 1985
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phenomenology of prolonged febrile seizures: results of the FEBSTAT study.

Neurology·2008
Same author

Biomarkers of HIV-1 CNS infection and injury.

Neurology·2007
Same author

Whole brain and localized magnetization transfer measurements are associated with cognitive impairment in patients infected with human immunodeficiency virus.

AJNR. American journal of neuroradiology·2007
Same author

Updated research nosology for HIV-associated neurocognitive disorders.

Neurology·2007
Same author

Monocyte chemoattractant protein-1 correlates with subcortical brain injury in HIV infection.

Neurology·2006
Same author

Bone marrow diffusion measures correlate with dementia severity in HIV patients.

AJNR. American journal of neuroradiology·2006
Same journal

Impact of Postpandemic Pediatric Infection Rebound on Febrile Seizures: A Nationwide Cohort Study, 2013-2023.

Pediatric neurology·2026
Same journal

The Hidden Cost of Developmental and Epileptic Encephalopathy in Australia: Caregiver Quality of Life, Sleep, Depression, and Workforce Participation.

Pediatric neurology·2026
Same journal

A Novel Neonatal Brain Injury Score for Infants With Congenital Diaphragmatic Hernia.

Pediatric neurology·2026
Same journal

Clinical and Functional Severity of Cerebral Palsy in a Tertiary Referral Cohort From Northeast Brazil: Insights From a Middle-Income Country.

Pediatric neurology·2026
Same journal

Small-Fiber Neuropathy in an Adolescent With Prader-Willi Syndrome.

Pediatric neurology·2026
Same journal

Research of Tuberous Sclerosis Complex (TSC)-Associated Neuropsychiatric Disorders (TAND) in China.

Pediatric neurology·2026
See all related articles

Shunt malfunction in a teenage girl caused Parkinsonism due to aqueductal stenosis. Treatment with levodopa and shunt revision successfully resolved her symptoms.

Area of Science:

  • Neurology
  • Neurosurgery
  • Pediatric Neurology

Background:

  • Aqueductal stenosis is a condition characterized by the obstruction of the cerebral aqueduct, leading to cerebrospinal fluid (CSF) buildup and increased intracranial pressure.
  • Shunt systems are often implanted to manage hydrocephalus, a common complication of aqueductal stenosis, by diverting excess CSF.
  • Shunt malfunction can occur, potentially leading to neurological complications.

Observation:

  • A 16-year-old female patient presented with symptoms indicative of Parkinsonism.
  • The patient had a history of aqueductal stenosis, a known risk factor for hydrocephalus.
  • The onset of Parkinsonism was temporally associated with a shunt malfunction.

Findings:

  • Parkinsonism, characterized by motor impairments, developed secondary to shunt malfunction in a patient with aqueductal stenosis.

Related Experiment Videos

  • The patient's Parkinsonian symptoms showed a positive response to levodopa, a medication used to treat Parkinson's disease.
  • Surgical revision of the malfunctioning shunt led to the resolution of the patient's symptoms.

    • Implications:

    • This case highlights a rare but significant neurological complication of shunt malfunction in patients with aqueductal stenosis.
    • The findings suggest that shunt malfunction should be considered in the differential diagnosis of Parkinsonism in patients with hydrocephalus.
    • Further investigation into the pathogenetic mechanisms linking shunt malfunction, CSF dynamics, and Parkinsonism is warranted.