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Related Experiment Video

Updated: Jun 25, 2025

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

[Renal involvement in systemic diseases].

¹Klinisches Institut für Pathologie, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich. renate.kain@meduniwien.ac.at.

Pathologie (Heidelberg, Germany)

|May 28, 2024

Summary

Non-neoplastic kidney diseases can mimic autoimmune kidney conditions. This review covers antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and systemic lupus erythematosus (SLE), discussing new diagnostic and treatment strategies.

Keywords:

Antineutrophil cytoplasmic antibodies Glomerulonephritis Immune checkpoint inhibitors Systemic lupus erythematosus Vasculitis

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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Published on: June 16, 2020

Area of Science:

Nephrology
Immunology
Internal Medicine

Background:

Non-neoplastic renal parenchyma diseases can present as systemic disorders.
These conditions are crucial in the differential diagnosis of autoimmune kidney diseases.
Understanding these overlaps is key for accurate diagnosis and management.

Purpose of the Study:

To present antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and systemic lupus erythematosus (SLE) as common autoimmune kidney diseases.
To contextualize AAV and SLE within the broader spectrum of renal diseases.
To explore novel diagnostic and therapeutic advancements for these conditions.

Main Methods:

Literature review of recent studies.
Overview of clinical presentations of AAV and SLE.
Synthesis of current knowledge on diagnostic and therapeutic approaches.

Main Results:

Systemic disorders can manifest as non-neoplastic renal diseases, complicating diagnosis.
ANCA-associated vasculitis and SLE are significant autoimmune kidney diseases with distinct features.
Emerging diagnostic tools and targeted therapies are improving patient outcomes.

Conclusions:

Accurate differentiation between non-neoplastic and autoimmune renal diseases is essential.
Advances in diagnostics and therapeutics offer new hope for managing AAV and SLE.
Continued research is vital for refining treatment strategies in autoimmune nephrology.