Related Experiment Video

Updated: Jun 25, 2025

Guided Differentiation of Mature Kidney Podocytes from Human Induced Pluripotent Stem Cells Under Chemically Defined Conditions
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Guided Differentiation of Mature Kidney Podocytes from Human Induced Pluripotent Stem Cells Under Chemically Defined Conditions

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Dach1 is essential for maintaining normal mature podocytes.

Keiko Tanaka1,2, Haruko Hayasaka3, Taiji Matsusaka1

  • 1Departments of Physiology, Tokai University School of Medicine, Kanagawa, Japan.

Plos One
|May 28, 2024
PubMed
Summary

Dach1 is crucial for mature podocyte integrity. Loss of Dach1 in adult mice leads to albuminuria and glomerulosclerosis, highlighting its role in kidney health.

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