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ALS-associated VRK1 R321C mutation causes proteostatic imbalance and mitochondrial defects in iPSC-derived motor

D Oliveira1, A F Assoni2, L M Alves2

  • 1Human Genome and Stem Cell Research Center, Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil; School of Medical Sciences Santa Casa and Pathological Sciences Unit, Irmandade Santa Casa de Misericordia de Sao Paulo, Sao Paulo, Brazil.

Neurobiology of Disease
|May 28, 2024
PubMed

Keywords:
Amyotrophic lateral sclerosisAutosomal recessive inheritanceNeurogeneticsVRK1

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