Jove
Visualize
Contact Us

Related Concept Videos

Neural Circuits01:25

Neural Circuits

1.2K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.2K
Neuron Structure01:30

Neuron Structure

12.8K
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
12.8K
Electrical Synapses01:28

Electrical Synapses

8.3K
Electrical synapses found in all nervous systems play important and unique roles. In these synapses, the presynaptic and postsynaptic membranes are very close together (3.5 nm) and are actually physically connected by channel proteins forming gap junctions.
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
8.3K
Neuronal Communication01:28

Neuronal Communication

843
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
843
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

3.2K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
3.2K
Action Potential01:31

Action Potential

7.9K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they...
7.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

LHX2 regulates biophysical properties of astrocytes in the postnatal mouse hippocampus.

Journal of neurophysiology·2026
Same author

How heterogeneity shapes dynamics and computation in the brain.

Neuron·2025
Same author

Degeneracy Explains Diversity in Interneuronal Regulation of Pattern Separation in Heterogeneous Dentate Gyrus Networks.

Function (Oxford, England)·2025
Same author

LHX2 regulates dendritic morphogenesis in layer II/III neurons of the neocortex.

Science advances·2025
Same author

The transcription factor LHX2 suppresses astrocyte proliferation in the postnatal mammalian cerebral cortex.

Development (Cambridge, England)·2025
Same author

The Brain's Best Kept Secret Is Its Degenerate Structure.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 25, 2025

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
10:32

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

Published on: April 15, 2015

8.5K

Network motifs in cellular neurophysiology.

Divyansh Mittal1, Rishikesh Narayanan2

  • 1Centre for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.

Trends in Neurosciences
|May 28, 2024
PubMed
Summary

Network motifs, a concept from network science, reveal the functional architecture within single neurons. These computational building blocks explain key cellular neurophysiology processes and adaptations.

Keywords:
complex systemdegeneracydendritefeedbackneural computationneuronal plasticity

More Related Videos

Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes
09:36

Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes

Published on: March 23, 2011

13.0K
Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions
07:38

Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions

Published on: June 7, 2024

1.5K

Related Experiment Videos

Last Updated: Jun 25, 2025

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
10:32

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

Published on: April 15, 2015

8.5K
Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes
09:36

Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes

Published on: March 23, 2011

13.0K
Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions
07:38

Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions

Published on: June 7, 2024

1.5K

Area of Science:

  • Neuroscience
  • Network Science
  • Graph Theory

Background:

  • Network science and graph theory, particularly network motifs, are increasingly used to study complex biological systems like neuronal networks.
  • Network-based approaches can model individual neuron functions by representing cellular elements (e.g., ion channels, membrane voltage) as nodes and interactions as edges.

Purpose of the Study:

  • To present a case for network motifs as tools for defining the functional architecture of single-neuron physiology and adaptations.
  • To highlight the role of computational motifs in cellular neurophysiology.

Main Methods:

  • Review of existing literature applying network science concepts to neuronal function.
  • Conceptualization of cellular elements and interactions within a network framework.

Main Results:

  • Network motifs serve as functional building blocks illuminating principles of cellular neurophysiology.
  • Computational motifs are present in mechanisms of action potential generation, neuronal oscillations, dendritic integration, and neuronal plasticity.

Conclusions:

  • Network motifs offer a powerful perspective for understanding the functional architecture and adaptive capabilities of single neurons.
  • Future research using the network motif framework may elucidate neuronal complexities in health and disease.