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Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
Published on: September 30, 2016
Research advances on TIL therapy for colorectal cancer
Jiaojiao Jiang1, Wenxi Shu1, Qinghua Yao2
1The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Abstract:
Colorectal cancer (CRC) is a prevalent gastrointestinal malignancy. Tumor-infiltrating lymphocyte (TIL) therapy, a form of adoptive cellular therapy (ACT), involves isolating T lymphocytes from tumor tissues, in vitro expansion, and reintroduction into the body to target and eliminate tumor cells. This article presents an overview of the development and application of TIL therapy in CRC, as well as the associated challenges.
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