Related Experiment Video
Updated: Aug 6, 2026

08:52
Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
Published on: June 13, 2018
8.9K
Lymph node myeloid sarcoma with TP53‑associated myelodysplastic syndrome: A case report
1Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang 310006, P.R. China.
Oncology Letters
|May 29, 2024
Summary
Myeloid sarcoma (MS) is a rare cancer easily misdiagnosed. This case highlights TP53-mutated MS with myelodysplastic syndrome (MDS), emphasizing the need for prompt diagnosis and biopsy for better outcomes.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Myeloid sarcoma (MS) is an extramedullary tumor with high acute myeloid leukemia (AML) progression risk.
- MS often presents with non-specific symptoms, leading to frequent misdiagnosis.
- TP53 mutations and complex karyotypes are associated with poor prognosis in MS.

