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Frederik Neess Engsig1, Gitte Kronborg1,2

  • 1Infektionsmedicinsk Afdeling, Københavns Universitetshospital - Hvidovre Hospital.

Ugeskrift for Laeger
|May 29, 2024
PubMed
Summary
This summary is machine-generated.

Pre-exposure prophylaxis (PrEP) significantly lowers HIV transmission risk in high-risk groups. Its implementation in Denmark offers a path to potentially ending the HIV epidemic through accessible antiretroviral therapy.

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Pharmacology

Background:

  • Pre-exposure prophylaxis (PrEP) is a key strategy to reduce HIV transmission risk.
  • Antiretroviral drugs in a combination tablet, taken daily or on demand, constitute PrEP.
  • PrEP has been accessible in Denmark since 2019.

Purpose of the Study:

  • To review the implementation and effects of PrEP in Denmark.
  • To assess PrEP's role in reducing HIV transmission within the Danish context.

Main Methods:

  • Review of existing data on PrEP use and outcomes in Denmark.
  • Analysis of PrEP indications and provision by infectious disease specialists.

Main Results:

  • PrEP is indicated for men and transgender individuals engaging in unprotected anal intercourse with multiple male partners.

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  • Recent diagnoses of syphilis, chlamydia, or gonorrhea are also indications for PrEP.
  • The review summarizes the observed effects of PrEP in Denmark.

    • Conclusions:

    • Continued PrEP implementation can substantially decrease HIV transmission rates.
    • Widespread PrEP use holds the potential to end the HIV epidemic in Denmark.