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Camilla Dalby Hansen^1,2, Katrine Prier Lindvig^1,2, Henning Grønbæk^3,4

¹Center for Leverforskning, Afdeling for Medicinske Mavetarmsygdomme, Odense Universitetshospital.

Ugeskrift for Laeger

|May 29, 2024

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Fatty liver disease is now steatotic liver disease (SLD), encompassing MASLD, ALD, and MetALD. This renaming improves classification and reduces stigma, emphasizing early etiological identification for better patient outcomes.

Area of Science:

Hepatology
Gastroenterology
Liver Disease Research

Background:

The term "fatty liver disease" has been updated to "steatotic liver disease" (SLD) in 2023.
Steatotic liver disease (SLD) now encompasses metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and metabolic and alcohol-related liver disease (MetALD).

Purpose of the Study:

To review the recent renaming of fatty liver disease to steatotic liver disease (SLD).
To highlight the new classification including MASLD, ALD, and MetALD.
To emphasize the importance of identifying the etiological factors for improved prognosis and treatment.

Main Methods:

Literature review of recent nomenclature changes in liver disease.
Analysis of the implications of the new classification system.

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Discussion of the impact of renaming on clinical practice and patient stigma.

Main Results:

The nomenclature shift to steatotic liver disease (SLD) aims to integrate metabolic and alcohol-related factors more effectively.
The new classification (MASLD, ALD, MetALD) provides a more comprehensive framework for understanding liver conditions.
Reducing stigma associated with liver disease is a key objective of the renaming.

Conclusions:

The renaming to steatotic liver disease (SLD) offers a more accurate and less stigmatizing classification.
Early identification of the cause of SLD is crucial for effective patient management and prognosis.
Interventions targeting causative risk factors are essential for improving outcomes in patients with steatotic liver disease.