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Solid and papillary epithelial neoplasm of the pancreas
Radiology
|February 1, 1985
Summary
Solid and papillary epithelial neoplasm (SPEN) of the pancreas is a rare, low-grade malignant tumor distinct from ductal adenocarcinoma. SPEN is curable with surgery and often misdiagnosed, highlighting the need for accurate classification.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Radiology
Background:
- Solid and papillary epithelial neoplasm (SPEN) is an uncommon pancreatic tumor.
- It is histologically distinct from ductal adenocarcinoma and presents a low-grade malignancy.
- SPEN often occurs in young black women and is frequently misclassified.
Purpose of the Study:
- To review cases of SPEN.
- To describe the distinct histological and radiological features of SPEN.
- To emphasize its curability via surgical excision.
Main Methods:
- Review of twelve cases of SPEN.
- Analysis of histopathological findings.
- Evaluation of sonography and CT imaging characteristics.
Main Results:
- SPEN is a well-demarcated pancreatic mass.
- Imaging can show solid, mixed cystic/solid, or largely cystic appearances.
- Radiological presentation depends on tumor integrity and degenerative changes.
Conclusions:
- SPEN is a distinct clinicopathological entity.
- Accurate diagnosis is crucial for appropriate management.
- Surgical excision offers a curative option for SPEN.