Characterization and functional analysis of chicken CDK protein

Zhixuan Xiong1, Jingjing Cao2, Ke Wang3

  • 1Department of Veterinary Preventive Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, 430070, China.

Poultry Science
|May 29, 2024
PubMed
Summary

Chicken cell cycle-dependent kinases (CDKs), especially CDK6, suppress the innate immune response. These CDKs facilitate infectious bursal disease virus (IBDV) replication by inhibiting interferon-beta (IFN-β) production.

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