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Trace elements in human nutrition.

R E Burch, H K Hahn

    The Medical Clinics of North America
    |September 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    The importance of trace elements in human nutrition is gaining clinical recognition. New findings challenge previous beliefs about deficiency likelihood, highlighting the need for further research into these essential nutrients.

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    Area of Science:

    • Human nutrition
    • Clinical medicine
    • Biochemistry

    Background:

    • Trace elements are essential for human health, yet their clinical significance was historically underestimated.
    • Ubiquitous presence in nature led to a belief that deficiencies were rare, except in extreme circumstances.
    • The increasing use of total parenteral nutrition (TPN) has challenged this viewpoint.

    Purpose of the Study:

    • To highlight the growing clinical recognition of trace elements in human nutrition.
    • To discuss factors that have made previous assumptions about trace element deficiencies untenable.
    • To underscore the importance of identifying and understanding genetic disorders related to trace element metabolism.

    Main Methods:

    • Review of clinical observations and nutritional science literature.

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  • Analysis of the impact of total parenteral nutrition on trace element status.
  • Examination of genetic diseases affecting trace element metabolism.

    • Main Results:

    • Clinical awareness of trace element roles in nutrition is increasing.
    • Total parenteral nutrition practices necessitate a re-evaluation of trace element deficiency risks.
    • Genetic disorders like Menkes' kinky hair syndrome and acrodermatitis enteropathica underscore the clinical relevance of trace elements.

    Conclusions:

    • Trace elements are critical for human health and nutrition.
    • Further recognition and research into trace element metabolism and associated diseases are warranted.
    • Clinicians must consider trace element status, especially in patients receiving TPN or with specific genetic conditions.