The impact of cirrhosis on short and long postoperative outcomes after distal pancreatectomy
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View abstract on PubMed
Summary
This summary is machine-generated.Distal pancreatectomy in patients with compensated cirrhosis shows similar postoperative outcomes and survival rates compared to those without cirrhosis. However, cirrhotic patients experienced longer operative times.
Area Of Science
- Hepatology
- Surgical Oncology
- Gastroenterology
Background
- The impact of cirrhosis on distal pancreatectomy outcomes remains largely unreported.
- Evaluating postoperative results in cirrhotic patients undergoing this procedure is crucial.
Purpose Of The Study
- To assess the safety and outcomes of distal pancreatectomy in patients with cirrhosis.
- To compare postoperative complications and survival between cirrhotic and non-cirrhotic patients.
Main Methods
- Retrospective, multicentric study of patients undergoing distal pancreatectomy (2008-2020).
- Cirrhotic patients (n=32) were matched 1:4 with non-cirrhotic controls (n=128).
- Primary endpoint: severe morbidity (Clavien-Dindo grade ≥III); secondary endpoints: complications and survival.
Main Results
- Severe morbidity rates were comparable (28.13% vs 25.75%, P=.11).
- Operative time was significantly longer in the cirrhotic group (P=.01).
- Similar rates of pancreatic fistula, hemorrhage, reoperation, mortality, and long-term survival were observed.
Conclusions
- Distal pancreatectomy is feasible in patients with compensated cirrhosis when performed in high-volume centers.
- The procedure demonstrates acceptable safety profiles and survival outcomes in this patient population.
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