Venetoclax-associated interstitial pneumonitis
Related Experiment Video
Updated: Jun 25, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
1Department of Medicine, Division of Pulmonary and Critical Care, Houston Methodist Hospital, Houston, TX, Address: 6550 Fannin St., Houston, TX, 77030, USA.
Abstract:
Venetoclax is a selective inhibitor of the antiapoptotic protein B-cell lymphoma 2 (BCL-2). It is approved for the treatment of chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL) and acute myeloid leukemia (AML) in combination with chemotherapy or hypomethylating agents. Interstitial pneumonitis due to venetoclax has not been described in the literature. We describe a case of a 79-year-old female who experienced SLL relapse and developed interstitial pneumonitis associated with venetoclax, which completely resolved after discontinuation of the medication.
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