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Updated: Jun 25, 2025
Author Spotlight: Advancing Biopsy Techniques with Transesophageal Ultrasound
Published on: November 21, 2023
Contrast-enhanced guided endoscopic ultrasound procedures.
Marcel Ioan Gheorghiu1, Andrada Seicean2, Cristina Pojoga1,3
1Department of Gastroenterology, "Prof. Dr. Octavian Fodor" Regional Institute of Gastroenterology and Hepatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca 400162, Cluj, Romania.
Contrast-enhanced endoscopic ultrasound (CH-EUS) improves pancreatic lesion characterization by visualizing microvessels. While initially promising for tissue acquisition, its supplementary diagnostic value in pancreatic solid lesions remains unconfirmed by further studies.
Area of Science:
- Gastroenterology
- Medical Imaging
- Oncology
Background:
- Endoscopic ultrasound (EUS) limitations in visualizing inhomogeneous tumors are addressed by contrast enhancement.
- Contrast-enhanced EUS (CH-EUS) identifies microvessels, improving tumor characterization.
Purpose of the Study:
- To review current knowledge on contrast-guided EUS procedures for pancreatic lesions.
- To evaluate the diagnostic and therapeutic applications of CH-EUS.
Main Methods:
- Review of available data on contrast-guided EUS procedures.
- Analysis of indications for CH-EUS tissue acquisition and therapy.
Main Results:
- CH-EUS aids in differentiating isoechoic lesions and mural nodules.
- CH-EUS is indicated for drainage of pancreatic fluid collections/bile ducts and visualizing non-visualized vessels.
- CH-EUS assesses post-ablation outcomes for pancreatic neuroendocrine tumors.
Conclusions:
- CH-EUS offers specific indications for tissue acquisition and therapy in pancreatic diseases.
- While not universally superior for tissue sampling, CH-EUS provides valuable insights in select cases.
- CH-EUS plays a role in therapeutic guidance and immediate post-treatment assessment.
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