Osteoporosis in a Woman With Multiple Sclerosis: A Case Report

Area of Science:

• Neurology
• Rheumatology
• Orthopedics

Background:

• Multiple sclerosis (MS) is a progressive autoimmune disorder affecting the central nervous system.
• MS is increasingly associated with systemic complications, including severe osteoporosis.
• Osteoporosis in MS patients can lead to debilitating fractures and reduced mobility.

Observation:

• A 63-year-old female with a history of MS developed a right femur fracture.
• She underwent total hip arthroplasty, and osteoporosis was diagnosed and treated.
• A subsequent periprosthetic femoral fracture occurred, requiring surgical fixation.

Findings:

• The patient experienced multiple fractures secondary to severe osteoporosis in the context of MS.
• Treatment involved surgical interventions and bisphosphonate administration.
• Despite complications, the patient regained independent ambulation with difficulty.

Implications:

• This case underscores the critical need for vigilant osteoporosis screening and management in multiple sclerosis patients.
• Aggressive management of osteoporosis is essential to prevent fractures and maintain mobility in this population.
• Further research into the interplay between MS and bone metabolism is warranted.