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Emergency Department Evaluation of Young Infants With Head Injury
Todd W Lyons1,2, Rebekah Mannix1,2, Michael C Monuteaux3,2
1Departments of Pediatrics and Emergency Medicine.
Insights
Young infants (<3 months) with head injuries face higher risks of diagnostic imaging, traumatic brain injury (TBI) diagnosis, and mortality compared to older children. This highlights the need for specialized care for these vulnerable infants.
Area of Science:
- Pediatric Emergency Medicine
- Neurotrauma Research
- Public Health
Background:
- Head injuries in young children require careful evaluation in emergency departments (EDs).
- Infants, particularly those under 3 months, represent a vulnerable population with unique physiological considerations.
Purpose of the Study:
- To compare the emergency department (ED) evaluation and outcomes of young head-injured infants (<3 months) with those of older children (3-24 months).
- To identify disparities in diagnostic imaging utilization, traumatic brain injury (TBI) diagnosis, and mortality rates between these age groups.
Main Methods:
- Retrospective, cross-sectional analysis of the Pediatric Health Information Systems database (2015-2019).
- Inclusion of children under 2 years old with isolated head injuries across 47 EDs.
- Primary outcome: diagnostic cranial imaging. Secondary outcomes: TBI diagnosis, clinically important TBI, and mortality.
Main Results:
- Youngest infants (<3 months) were significantly more likely to undergo cranial imaging (50.3% vs 18.3%) compared to older children (12-23 months).
- Infants <3 months had higher rates of TBI diagnosis (17.5% vs 2.7%), clinically important TBI (4.6% vs 0.5%), and mortality (0.3% vs 0.1%).
- Among those with imaging, TBI was more common in the youngest infants (26.4% vs 8.8%).
Conclusions:
- Young infants with head injuries exhibit significantly higher rates of cranial imaging, TBI diagnosis, and mortality.
- These findings underscore the critical need for specialized evaluation and management protocols for head-injured infants.
- Further research into age-specific risk factors and optimal diagnostic strategies is warranted.
Objectives:
We compared the emergency department (ED) evaluation and outcomes of young head-injured infants to older children.
Methods:
Using the Pediatric Health Information Systems database, we performed a retrospective, cross-sectional analysis of children <2 years old with isolated head injuries (International Classification of Diseases, 10th Revision, diagnoses) at one of 47 EDs from 2015 to 2019. Our primary outcome was utilization of diagnostic cranial imaging. Secondary outcomes were diagnosis of traumatic brain injury (TBI), clinically important TBI, and mortality. We compared outcomes between the youngest infants (<3 months old) and children 3 to 24 months old.
Results:
We identified 112 885 ED visits for children <2 years old with isolated head injuries. A total of 62 129 (55%) were by males, and 10 325 (9.1%) were by infants <3 months of age. Compared with older children (12-23 months old), the youngest infants were more likely to: Undergo any diagnostic cranial imaging (50.3% vs 18.3%; difference 31.9%, 95% confidence interval [CI] 35.0-28.9%), be diagnosed with a TBI (17.5% vs 2.7%; difference 14.8%, 95% CI 16.4%-13.2%) or clinically important TBI (4.6% vs 0.5%; difference 4.1%, 95% CI 3.8%-4.5%), and to die (0.3% vs 0.1%; difference 0.2%, 95% CI 0.3%-0.1%). Among those undergoing computed tomography or MRI, TBIs were significantly more common in the youngest infants (26.4% vs 8.8%, difference 17.6%, 95% CI 16.3%-19.0%).
Conclusions:
The youngest infants with head injuries are significantly more likely to undergo cranial imaging, be diagnosed with brain injuries, and die, highlighting the need for a specialized approach for this vulnerable population.
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