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Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy
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Nonclinical Safety Testing of RNA Vaccines
1The NCD Company, Polling, Germany. mail@gundel-hager.de.
Methods in Molecular Biology (Clifton, N.J.)
|May 30, 2024
Abstract:
In this chapter, we will first consider the overall goal of nonclinical safety testing during drug development and have a brief overview of its regulatory background. We will then discuss some basic requirements of safety/toxicity testing before concentrating on the safety testing of RNA vaccines and developing a sample RNA vaccine safety testing program.
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