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Related Concept Videos

Nursing Ethical Principles II01:27

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Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
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  1. Home
  3. Research Domains
  5. Language, Communication And Culture
  7. Cultural Studies
  9. Postcolonial Studies
  11. Family Communication Of Cancer Genetic Test Results In An Ethnically Diverse Population: A Qualitative Exploration Of More Than 200 Patients.
  1. Home
  3. Research Domains
  5. Language, Communication And Culture
  7. Cultural Studies
  9. Postcolonial Studies
  11. Family Communication Of Cancer Genetic Test Results In An Ethnically Diverse Population: A Qualitative Exploration Of More Than 200 Patients.

Related Experiment Video

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
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Published on: May 10, 2024

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Family communication of cancer genetic test results in an ethnically diverse population: a qualitative exploration of more than 200 patients.

Rachel Hodan1,2, Miles Picus3, Caroline Stanclift3

  • 1Cancer Genetics and Genomics, Stanford Health Care, Stanford, CA, USA. rhodan@stanfordhealthcare.org.

Journal of Community Genetics
|May 30, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Communicating hereditary cancer multi-gene panel (MGP) results, including uncertain findings, is influenced by perceived utility and self-efficacy. Clinician reinforcement can improve patient intent to share genetic test results.

Keywords:
Cancer geneticsFamily communicationGenetic counselingGermline genetic test results

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Area of Science:

  • Genetics
  • Medical Sociology
  • Behavioral Science

Background:

  • Previous research on cancer genetic test result communication focused on high-risk pathogenic variants (PV) in White populations.
  • Limited data exist on communicating moderate-risk PVs, variants of uncertain significance (VUS), and negative results.
  • This study addresses communication of diverse hereditary cancer multi-gene panel (MGP) results in a diverse population.

Purpose of the Study:

  • To examine the communication of positive, negative, and VUS hereditary cancer MGP results.
  • To explore factors influencing patient communication of genetic test results in an ethnically and socioeconomically diverse population.
  • To apply the Theory of Planned Behavior (TPB) to understand communication patterns.

Main Methods:

  • Qualitative content and thematic analysis of free-text survey responses.
  • Utilized data from 214 respondents (256 responses) from a multicenter, prospective cohort study.
  • Analysis guided by the Theory of Planned Behavior (TPB).

    • Main Results:

    • High perceived utility of sharing genetic results correlated with positive attitudes and encouragement for others to test.
    • High self-efficacy in sharing was linked to high perceived utility.
    • Low self-efficacy was associated with VUS results and uncertainty about sharing.

    Conclusions:

    • Clinician reinforcement of genetic testing utility may increase patient intent to communicate results.
    • Strategies to improve patient understanding of VUS results are crucial.
    • Addressing self-efficacy and perceived utility can enhance family communication of genetic test results.