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Stability of clozapine tablets repackaged in dose administration aids using repackaging machines

Marion Emonet1, Antony Citterio-Quentin2, Sandrine Bourgeois3

  • 1Pharmacy Department, The Vinatier Hospital, Bron, France.

European Journal of Hospital Pharmacy : Science and Practice
|May 30, 2024
PubMed
Summary

Repackaged clozapine tablets remained chemically stable for 84 days, meeting mass uniformity standards. However, physical tests revealed cracking and reduced hardness, leading to an 84-day shelf life.

Keywords:
Chemistry, PharmaceuticalDrug CompoundingDrug stabilityPharmacopoeiaSafety

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