Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Single cells and rapid inward sodium current.

T Powell

    Advances in Myocardiology
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Researchers reviewed measurements of rapid inward sodium current in cardiac cells. Improved voltage control allowed the first recordings of sodium current activation and inactivation phases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Impact of the T2-weighted axial oblique MRI sequence in the assessment of peroneal tendons.

    Clinical radiology·2020
    Same author

    The Cascading Effects of Externalizing Behaviors and Academic Achievement Across Developmental Transitions: Implications for Prevention and Intervention.

    Prevention science : the official journal of the Society for Prevention Research·2019
    Same author

    Developmental cascades of social competence, achievement in school, and achievement on standardized assessments during the transition to adolescence and secondary school.

    Journal of adolescence·2019
    Same author

    Disability, depression and suicide ideation in people with multiple sclerosis.

    Journal of affective disorders·2016
    Same author

    IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid.

    Placenta·2016
    Same author

    IFPA meeting 2015 workshop report I: placental mitochondrial function, transport systems and epigenetics.

    Placenta·2015

    Area of Science:

    • Cardiology
    • Electrophysiology
    • Cellular Biology

    Background:

    • The rapid inward sodium current is crucial for cardiac function.
    • Previous studies faced challenges in precise voltage control for measurements.
    • Single cardiac cells offer a simplified model for electrophysiological studies.

    Purpose of the Study:

    • To review methods for measuring rapid inward sodium current in single cardiac cells.
    • To highlight advancements in voltage control for improved current recordings.
    • To present the first recordings of sodium current activation and inactivation phases.

    Main Methods:

    • Utilizing the simplified morphology of single cardiac cells.
    • Implementing improved spatial and temporal voltage control techniques.

    Related Experiment Videos

  • Recording the rapid inward sodium current.

    • Main Results:

    • Achieved superior spatial and temporal voltage control.
    • Successfully recorded both activation and inactivation phases of the rapid inward sodium current.
    • Demonstrated the utility of simplified cell models for detailed current analysis.

    Conclusions:

    • Simplified cardiac cell models facilitate precise electrophysiological measurements.
    • Advanced voltage control enables detailed characterization of ion currents.
    • These findings are relevant for understanding cellular cardiac function.