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Changes in the contralateral eye in uncomplicated persistent hyperplastic primary vitreous in adults
American Journal of Ophthalmology
|February 15, 1985
Summary
Persistent hyperplastic primary vitreous (PHPV) can occur with other serious eye conditions. Unilateral PHPV in adults may be associated with open-angle glaucoma and other ocular anomalies in the fellow eye.
Area of Science:
- Ophthalmology
- Medical Imaging
- Genetics
Background:
- Persistent hyperplastic primary vitreous (PHPV) is a rare congenital developmental anomaly of the eye.
- Typically diagnosed in infancy, PHPV can present atypically in adulthood.
- This study investigates adult cases of unilateral PHPV.
Observation:
- Two adult patients (62-year-old male, 71-year-old female) presented with unilateral PHPV.
- Diagnosis was confirmed via clinical examination and ultrasonography.
- The contralateral, unaffected eyes exhibited significant ocular abnormalities.
Findings:
- The contralateral eyes showed open-angle glaucoma.
- Anomalous blood vessels were observed throughout the anterior chamber angle circumference.
- Band keratopathy and heterochromia iridis were also noted in the unaffected eyes.
- A slight axial length difference (0.85 mm) was measured between the involved and uninvolved eyes.
Implications:
- Adult-onset unilateral PHPV may indicate a predisposition to other ocular pathologies.
- Associated conditions like glaucoma and vascular anomalies require careful monitoring.
- Ultrasonography is a valuable tool for diagnosing PHPV and assessing associated ocular structures.