Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Working Memory01:24

Working Memory

1.3K
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
1.3K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.5K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of TMS on the Decoding and Electrophysiology of Priority in Working Memory.

eNeuro·2026
Same author

Prioritization in working memory reduces interference via a beta band-linked transformation of the not-selected item.

bioRxiv : the preprint server for biology·2026
Same author

Revisiting alpha-theta cross-frequency dynamics during working memory.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same author

Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex?

Nature neuroscience·2025
Same author

Beta-band frequency shifts signal decisions in human prefrontal cortex.

iScience·2025
Same author

Distinct alpha networks modulate different aspects of perceptual decision-making.

PLoS biology·2025

Related Experiment Video

Updated: May 1, 2026

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course
11:33

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Published on: July 18, 2014

43.0K

Single-pulse Transcranial Magnetic Stimulation Affects Working-memory Performance via Posterior Beta-band

Jacqueline M Fulvio1, Saskia Haegens2,3,4, Bradley R Postle1

  • 1University of Wisconsin-Madison.

Journal of Cognitive Neuroscience
|May 31, 2024
PubMed
Summary

Single pulse transcranial magnetic stimulation (spTMS) modulates beta-band activity in working memory, disrupting priority coding rather than activating silent memories. This finding implicates beta-band dynamics in distinguishing prioritized from unprioritized information.

More Related Videos

Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation
00:08

Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation

Published on: August 20, 2019

14.3K
Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition
07:33

Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition

Published on: August 23, 2022

2.6K

Related Experiment Videos

Last Updated: May 1, 2026

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course
11:33

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Published on: July 18, 2014

43.0K
Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation
00:08

Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation

Published on: August 20, 2019

14.3K
Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition
07:33

Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition

Published on: August 23, 2022

2.6K

Area of Science:

  • Cognitive Neuroscience
  • Neuroimaging
  • Working Memory Research

Background:

  • Single pulse transcranial magnetic stimulation (spTMS) can temporarily restore the decodability of unprioritized memory items (UMIs) during working memory tasks.
  • This effect is associated with beta frequency band activity, suggesting its role in priority coding within working memory.
  • Previous theories proposed spTMS might activate 'activity-silent' memory traces.

Purpose of the Study:

  • To investigate the neural mechanisms underlying spTMS effects on working memory using electroencephalography (EEG).
  • To determine if spTMS activates silent neural sources or modulates ongoing neural activity.
  • To explore the role of beta-band dynamics in working memory priority coding and the impact of spTMS.

Main Methods:

  • EEG data from 12 participants performing a double serial retrocuing working-memory task with concurrent spTMS delivery were analyzed.
  • Spatially distributed Phase Coupling Extraction (SPCE) was used to decompose the EEG signal into coupled oscillators.
  • The temporal dynamics of component strength, particularly in the beta frequency band, were examined in relation to spTMS application and task performance.

Main Results:

  • spTMS did not activate previously silent neural sources; instead, it modulated ongoing activity.
  • spTMS exaggerated the decrease in strength of posterior beta components during the delay period.
  • The magnitude of spTMS's effect on posterior beta component strength correlated with performance disruption, especially on trials with UMI-lure probes.

Conclusions:

  • The findings challenge the 'activity-silent' hypothesis, suggesting spTMS disrupts working memory priority coding mechanisms.
  • Beta-band dynamics are implicated in distinguishing prioritized from unprioritized information in working memory.
  • spTMS's effect appears to be the disruption of this neural code, rather than the activation of dormant memory traces.